The average train between Düsseldorf and Melsungen takes 3h 56m and the fastest train takes 3h 48m. There is a train service every few hours from Düsseldorf to Melsungen. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Trains run hourly between Düsseldorf and Melsungen. The earliest departure is at 5:36 AM in the morning, and the last departure from Düsseldorf is at 8:36 PM which arrives into Melsungen at 12:33 AM. All services require a transfer, and take on average 3h 56m. The schedules shown below are for the next available departures.

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Want to know about travelling from Düsseldorf to Melsungen? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct train from Düsseldorf to Melsungen. However, there are services departing from Düsseldorf station and arriving at Melsungen station via Kassel-Wilhelmshoehe. The journey, including transfers, takes approximately 3h 56m.
Düsseldorf to Melsungen train services, operated by National Express, depart from Duesseldorf Hbf station.
Düsseldorf to Melsungen train services, operated by National Express, arrive at Kassel-Wilhelmshoehe station.
Book your Düsseldorf to Melsungen train tickets online with National Express, cantus Verkehrsgesellschaft mbH and Deutsche Bahn Intercity (DB IC).
The distance between Düsseldorf and Melsungen is 193.2 km. The road distance is 315 km.
National Express operates a train from Duesseldorf Hbf to Kassel-Wilhelmshoehe hourly, and the journey takes 3h 20m. Deutsche Bahn Intercity (DB IC) also services this route 5 times a day.