The average train between Düsseldorf and Speyer takes 2h 49m and the fastest train takes 2h 25m. The train service runs several times per day from Düsseldorf to Speyer. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Trains run every 4 hours between Düsseldorf and Speyer. The earliest departure is at 7:06 AM in the morning, and the last departure from Düsseldorf is at 11:28 PM which arrives into Speyer at 5:54 AM. All services require a transfer, and take on average 2h 49m. The schedules shown below are for the next available departures.

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Want to know about travelling from Düsseldorf to Speyer? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct train from Düsseldorf to Speyer. However, there are services departing from Düsseldorf station and arriving at Speyer station via Mannheim, Hauptbahnhof. The journey, including transfers, takes approximately 2h 49m.
Düsseldorf to Speyer train services, operated by Deutsche Bahn Intercity (DB IC), depart from Düsseldorf Hbf station.
Düsseldorf to Speyer train services, operated by Deutsche Bahn Intercity (DB IC), arrive at Mannheim, Hauptbahnhof station.
Book your Düsseldorf to Speyer train tickets online with Deutsche Bahn Intercity (DB IC) and Deutsche Bahn Regio (DB Regional).
The distance between Düsseldorf and Speyer is 241.9 km. The road distance is 303 km.
Deutsche Bahn Intercity (DB IC) operates a train from Düsseldorf Hbf to Mannheim, Hauptbahnhof hourly. Tickets cost €50–230 and the journey takes 1h 59m. Nederlandse Spoorwegen (NS) also services this route 5 times a day.