The average train between Darmstadt and Enschede takes 6h and the fastest train takes 5h 17m. There is a train service every few hours from Darmstadt to Enschede. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Trains run hourly between Darmstadt and Enschede. The earliest departure is at 3:35 AM at night, and the last departure from Darmstadt is at 6:34 PM which arrives into Enschede at 7:57 AM. All services require a transfer at Frankfurt and take an average of 6h. The schedules shown below are for the next available departures.



5h 20m • 3 changes



5h 27m • 3 changes



5h 17m • 3 changes



5h 27m • 3 changes



6h 22m • 3 changes



5h 52m • 3 changes



5h 20m • 3 changes



5h 27m • 3 changes



6h 22m • 3 changes



5h 52m • 3 changes



5h 20m • 3 changes



5h 27m • 3 changes



6h 22m • 3 changes



5h 52m • 3 changes



5h 20m • 3 changes



5h 27m • 3 changes
Want to know about travelling from Darmstadt to Enschede? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct train from Darmstadt to Enschede. However, there are services departing from Darmstadt station and arriving at Enschede station via Dortmund Hbf. The journey, including transfers, takes approximately 6h.
Darmstadt to Enschede train services, operated by Deutsche Bahn Intercity (DB IC), depart from Frankfurt station.
Darmstadt to Enschede train services, operated by Deutsche Bahn Intercity (DB IC), arrive at Enschede station.
Book your Darmstadt to Enschede train tickets online with Deutsche Bahn Intercity (DB IC) and Deutsche Bahn Regio (DB Regional).
The distance between Darmstadt and Enschede is 288.3 km. The road distance is 418 km.
You can take a bus from Darmstadt Luisenplatz to Enschede via Frankfurt, Frankfurt, and Dortmund Hbf in around 5h 59m.