The average train between Derby and High Wycombe takes 2h 41m and the fastest train takes 2h 20m. The train service runs several times per day from Derby to High Wycombe. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Trains run every 4 hours between Derby and High Wycombe. The earliest departure is at 7:51 AM in the morning, and the last departure from Derby is at 5:54 PM which arrives into High Wycombe at 8:18 PM. All services require a transfer, and take on average 2h 41m. The schedules shown below are for the next available departures.

2h 57m • 1 change

2h 56m • 1 change

2h 54m • 1 change

2h 54m • 1 change

2h 57m • 1 change

2h 56m • 1 change

2h 54m • 1 change

2h 54m • 1 change

2h 57m • 1 change

2h 56m • 1 change

2h 54m • 1 change

2h 54m • 1 change

2h 57m • 1 change

2h 56m • 1 change

2h 54m • 1 change

2h 54m • 1 change

2h 57m • 1 change

2h 56m • 1 change

2h 54m • 1 change

2h 54m • 1 change

2h 20m • 1 change

2h 25m • 1 change

2h 21m • 1 change

2h 25m • 1 change
Want to know about travelling from Derby to High Wycombe? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct train from Derby to High Wycombe. However, there are services departing from Derby station and arriving at High Wycombe station via Banbury. The journey, including transfers, takes approximately 2h 41m.
Derby to High Wycombe train services, operated by Cross Country, depart from Derby station.
Derby to High Wycombe train services, operated by Cross Country, arrive at High Wycombe station.
Book your Derby to High Wycombe train tickets online with Cross Country and Chiltern Railways.
The distance between Derby and High Wycombe is 152.1 km. The road distance is 197 km.
You can take a train from Derby to High Wycombe via Banbury in around 2h 31m.