The average train between Derby and Manchester Central Station takes 1h 52m and the fastest train takes 1h 35m. There is an hourly train service from Derby to Manchester Central Station. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Trains run hourly between Derby and Manchester Central Station. The earliest departure is at 12:10 AM at night, and the last departure from Derby is at 9:32 PM which arrives into Manchester Central Station at 11:12 PM. All services require a transfer at Sheffield and take an average of 1h 52m. The schedules shown below are for the next available departures.

1h 39m • 1 change

1h 38m • 1 change

1h 39m • 1 change

1h 50m • 1 change

5h 58m • 1 change

1h 54m • 1 change

1h 39m • 1 change

1h 54m • 1 change

5h 58m • 1 change

1h 54m • 1 change

1h 52m • 1 change

1h 54m • 1 change
Want to know about travelling from Derby to Manchester Central Station? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct train from Derby to Manchester Central Station. However, there are services departing from Derby station and arriving at Manchester Central Station station via Sheffield. The journey, including transfers, takes approximately 1h 52m.
Derby to Manchester Central Station train services, operated by Cross Country, depart from Derby station.
Derby to Manchester Central Station train services, operated by Cross Country, arrive at Manchester Oxford Road station.
Book your Derby to Manchester Central Station train tickets online with Cross Country, East Midlands Railways and TransPennine Express.
The distance between Derby and Manchester Central Station is 80.1 km. The road distance is 128 km.
You can take a train from Derby to Manchester Central Station via Sheffield and Manchester Oxford Road in around 1h 56m.