The average train between Dessau and Karlsruhe takes 6h 27m and the fastest train takes 5h 5m. There is a train service every few hours from Dessau to Karlsruhe. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Trains run hourly between Dessau and Karlsruhe. The earliest departure is at 4:06 AM at night, and the last departure from Dessau is at 10:59 PM which arrives into Karlsruhe at 9:09 AM. All services require a transfer at Leipzig Hbf and take an average of 6h 27m. The schedules shown below are for the next available departures.



7h 17m • 3 changes


5h 46m • 3 changes


5h 5m • 3 changes


5h 46m • 3 changes


5h 46m • 3 changes


5h 5m • 3 changes


5h 46m • 3 changes


6h 7m • 3 changes


5h 53m • 3 changes


5h 53m • 3 changes


5h 5m • 3 changes


5h 53m • 3 changes


5h 53m • 3 changes


5h 53m • 3 changes


5h 5m • 3 changes


5h 53m • 3 changesWant to know about travelling from Dessau to Karlsruhe? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct train from Dessau to Karlsruhe. However, there are services departing from Dessau station and arriving at Karlsruhe station via Leipzig Hbf. The journey, including transfers, takes approximately 6h 27m.
Dessau to Karlsruhe train services, operated by Deutsche Bahn Regio (DB Regional), depart from Dessau Hbf station.
Dessau to Karlsruhe train services, operated by Deutsche Bahn Regio (DB Regional), arrive at Karlsruhe Hauptbahnhof station.
Book your Dessau to Karlsruhe train tickets online with Deutsche Bahn Regio (DB Regional), Deutsche Bahn Intercity (DB IC) and LEO Express.
The distance between Dessau and Karlsruhe is 415.8 km. The road distance is 568 km.
You can take a train from Dessau Hbf to Karlsruhe Hauptbahnhof via Leipzig Hbf, Erfurt Hbf, and Frankfurt in around 6h 14m.