The average train between Detroit and St. Louis takes 14h 45m and the fastest train takes 10h 50m. The train service runs several times per day from Detroit to St. Louis. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Trains run twice daily between Detroit and St. Louis. The earliest departure is at 9:35 AM in the morning, and the last departure from Detroit is at 6:11 PM which arrives into St. Louis at 12:01 PM. All services require a transfer, and take on average 14h 45m. The schedules shown below are for the next available departures.
Want to know about travelling from Detroit to St. Louis? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct train from Detroit to St. Louis. However, there are services departing from Detroit station and arriving at St. Louis station via Chicago Union Station station. The journey, including transfers, takes approximately 14h 45m.
Detroit to St. Louis train services, operated by Amtrak, depart from Detroit station.
Detroit to St. Louis train services, operated by Amtrak, arrive at St. Louis station.
Book your Detroit to St. Louis train tickets online with Amtrak.
The distance between Detroit and St. Louis is 731.4 km. The road distance is 903 km.
You can take a train from Detroit to St. Louis via Chicago Union Station in around 10h 52m.
