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Domodossola (Station) to Lyon trains

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Trip Overview

The average train between Domodossola (Station) and Lyon takes 11h 4m and the fastest train takes 7h 34m. The train runs, on average, 2 times per week from Domodossola (Station) to Lyon. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.

11h 4m
Duration
399 km
Distance
€121
Average price
Twice a week
Frequency

Domodossola (Station) to Lyon train times

Trains run twice a week between Domodossola (Station) and Lyon. The earliest departure is at 9:48 AM in the morning, and the last departure from Domodossola (Station) is at 8:48 PM which arrives into Lyon at 11:22 AM. All services require a transfer at Genève and take an average of 11h 4m. The schedules shown below are for the next available departures.

Departing Friday, November 6, 2026

  •  → 

    Arrives next day

    Trenitalia EuroCitySwiss Federal Railways (SBB CFF FFS)Société Nationale des Chemins de fer Français (SNCF)14h 34m • 2 changes

Departing Saturday, November 7, 2026

  •  → 

    Trenitalia EuroCitySwiss Federal Railways (SBB CFF FFS)Société Nationale des Chemins de fer Français (SNCF)7h 34m • 2 changes

Frequently asked questions

Want to know about travelling from Domodossola (Station) to Lyon? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.

Map of how to get from Domodossola (Station) to Lyon.ExpandLaunch map view
  • Distance: 398.6 km
  • Duration: 11h 4m

What companies run services between Domodossola (Station), Piemonte, Italy and Lyon, France?

You can take a train from Domodossola to Lyon Part Dieu via Genève and Bellegarde in around 5h 55m.

Operators