Domodossola to Brussels Trains

Domodossola to Brussels trains

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Trip Overview

The average train between Domodossola and Brussels takes 14h 6m and the fastest train takes 10h 51m. The train service runs several times per day from Domodossola to Brussels. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.

14h 6m

Duration

968 km

Distance

€209

Average price

Twice daily

Frequency

Domodossola to Brussels train times

Trains run twice daily between Domodossola and Brussels. The earliest departure is at 4:35 AM at night, and the last departure from Domodossola is at 6:48 PM which arrives into Brussels at 11:26 AM. All services require a transfer at Brig and take an average of 14h 6m. The schedules shown below are for the next available departures.

Departing Wednesday, October 21, 2026

4:48 PM → 9:26 AM
Arrives next day
16h 38m • 3 changes
6:48 PM → 11:26 AM
Arrives next day
16h 38m • 3 changes

Departing Thursday, October 22, 2026

4:35 AM → 3:26 PM
10h 51m • 3 changes
5:54 AM → 5:26 PM
11h 32m • 3 changes
9:48 AM → 9:26 PM
11h 38m • 3 changes
4:48 PM → 9:26 AM
Arrives next day
16h 38m • 3 changes
Show more

Departing Friday, October 23, 2026

4:35 AM → 3:26 PM
10h 51m • 3 changes
5:54 AM → 5:26 PM
11h 32m • 3 changes
9:48 AM → 9:26 PM
11h 38m • 3 changes

Frequently asked questions

Want to know about travelling from Domodossola to Brussels? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.