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Domodossola to Florence trains

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Trip Overview

The average train between Domodossola and Florence takes 6h 8m and the fastest train takes 4h 10m. The train service runs several times per day from Domodossola to Florence. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.

6h 8m
Duration
426 km
Distance
€59
Average price
4 times a day
Frequency

Train

best
  1. Take the train from Domodossola to Milano P.Garibalditrain train Re
  2. Take the train from Milano Centrale to Firenze Santa Maria Novellatrain train 8111 / ...
5h 4m
€50–81

Domodossola to Florence train times

Trains run 4 times a day between Domodossola and Florence. The earliest departure is at 6:06 AM in the morning, and the last departure from Domodossola is at 8:06 PM which arrives into Florence at 7:35 AM. All services require a transfer at Milano P.Garibaldi and take an average of 6h 8m. The schedules shown below are for the next available departures.

Departing Thursday, November 5, 2026

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    TrenitaliaATMItaloTreno4h 29m • 2 changes

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    TrenitaliaATMItaloTreno4h 10m • 2 changes

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    Arrives next day

    TrenitaliaATMItaloTreno11h 29m • 2 changes

Departing Friday, November 6, 2026

  •  → 

    TrenitaliaATMItaloTreno4h 29m • 2 changes

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    TrenitaliaATMItaloTreno4h 10m • 2 changes

  •  → 

    Arrives next day

    TrenitaliaATMItaloTreno11h 29m • 2 changes

Departing Saturday, November 7, 2026

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    TrenitaliaATMItaloTreno4h 29m • 2 changes

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    TrenitaliaATMItaloTreno4h 10m • 2 changes

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    TrenitaliaATMItaloTreno4h 29m • 2 changes

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    TrenitaliaATMItaloTreno5h 29m • 2 changes
  • Show more

Departing Sunday, November 8, 2026

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    TrenitaliaATMItaloTreno4h 29m • 2 changes

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    TrenitaliaATMItaloTreno5h 29m • 2 changes

  •  → 

    TrenitaliaATMItaloTreno4h 29m • 2 changes

  •  → 

    TrenitaliaATMItaloTreno5h 29m • 2 changes
  • Show more

Departing Monday, November 9, 2026

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    TrenitaliaATMItaloTreno4h 29m • 2 changes

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    TrenitaliaATMItaloTreno4h 10m • 2 changes

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    Arrives next day

    TrenitaliaATMItaloTreno11h 29m • 2 changes

Departing Tuesday, November 10, 2026

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    TrenitaliaATMItaloTreno4h 29m • 2 changes

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    TrenitaliaATMItaloTreno4h 10m • 2 changes

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    Arrives next day

    TrenitaliaATMItaloTreno11h 29m • 2 changes

Departing Wednesday, November 11, 2026

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    TrenitaliaATMItaloTreno4h 29m • 2 changes

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    TrenitaliaATMItaloTreno4h 10m • 2 changes

Frequently asked questions

Want to know about travelling from Domodossola to Florence? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.

Map of how to get from Domodossola to Florence.ExpandLaunch map view
  • Distance: 426.2 km
  • Duration: 6h 8m

What companies run services between Domodossola, Italy and Florence, Italy?

You can take a train from Domodossola to Firenze Santa Maria Novella via Milano P.Garibaldi, Garibaldi Fs, Caiazzo, and Milano Centrale in around 5h 4m.

Operators