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Domodossola to Florence trains

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Trip Overview

The average train between Domodossola and Florence takes 6h 10m and the fastest train takes 4h 10m. The train service runs several times per day from Domodossola to Florence. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.

6h 10m
Duration
424 km
Distance
€61
Average price
4 times a day
Frequency

Train

best
  1. Take the train from Domodossola to Rho-Fiera Milanotrain train Re
  2. Take the train from Milano Rogoredo to Firenze Santa Maria Novellatrain train 9907 / ...
4h 34m
€48–78

Domodossola to Florence train times

Trains run 4 times a day between Domodossola and Florence. The earliest departure is at 6:06 AM in the morning, and the last departure from Domodossola is at 8:06 PM which arrives into Florence at 7:35 AM. All services require a transfer, and take on average 6h 10m. The schedules shown below are for the next available departures.

Departing Sunday, October 25, 2026

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    TrenitaliaItaloTreno4h 29m • 1 change

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    TrenitaliaItaloTreno4h 29m • 1 change

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    TrenitaliaItaloTreno5h 29m • 1 change

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    TrenitaliaItaloTreno4h 29m • 1 change
  • Show more

Departing Monday, October 26, 2026

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    TrenitaliaItaloTreno4h 29m • 1 change

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    TrenitaliaItaloTreno4h 10m • 1 change

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    Arrives next day

    TrenitaliaItaloTreno11h 29m • 1 change

Departing Tuesday, October 27, 2026

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    TrenitaliaItaloTreno4h 29m • 1 change

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    TrenitaliaItaloTreno4h 10m • 1 change

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    Arrives next day

    TrenitaliaItaloTreno11h 29m • 1 change

Departing Wednesday, October 28, 2026

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    TrenitaliaItaloTreno4h 29m • 1 change

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    TrenitaliaItaloTreno4h 10m • 1 change

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    Arrives next day

    TrenitaliaItaloTreno11h 29m • 1 change

Departing Thursday, October 29, 2026

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    TrenitaliaItaloTreno4h 29m • 1 change

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    TrenitaliaItaloTreno4h 10m • 1 change

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    Arrives next day

    TrenitaliaItaloTreno11h 29m • 1 change

Departing Friday, October 30, 2026

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    TrenitaliaItaloTreno4h 29m • 1 change

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    TrenitaliaItaloTreno4h 10m • 1 change

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    Arrives next day

    TrenitaliaItaloTreno11h 29m • 1 change

Departing Saturday, October 31, 2026

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    TrenitaliaItaloTreno4h 29m • 1 change

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    TrenitaliaItaloTreno4h 10m • 1 change

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    TrenitaliaItaloTreno4h 29m • 1 change

  •  → 

    TrenitaliaItaloTreno5h 29m • 1 change
  • Show more

Frequently asked questions

Want to know about travelling from Domodossola to Florence? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.

Map of how to get from Domodossola to Florence.ExpandLaunch map view
  • Distance: 423.8 km
  • Duration: 6h 10m

What companies run services between Domodossola, Italy and Florence, Italy?

You can take a train from Domodossola to Firenze Santa Maria Novella via Milano Rogoredo in around 4h 34m.

Operators