The average train between Domodossola and Lyss takes 2h 54m and the fastest train takes 2h 11m. There is a train service every few hours from Domodossola to Lyss. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Trains run hourly between Domodossola and Lyss. The earliest departure is at 4:35 AM at night, and the last departure from Domodossola is at 7:58 PM which arrives into Lyss at 11:22 PM. All services require a transfer at Spiez and take an average of 2h 54m. The schedules shown below are for the next available departures.


2h 54m • 2 changes


2h 54m • 2 changes


2h 34m • 2 changes


2h 54m • 2 changes


3h 17m • 2 changes


2h 54m • 2 changes


2h 54m • 2 changes


2h 54m • 2 changes


3h 17m • 2 changes


2h 54m • 2 changes


2h 54m • 2 changes


2h 54m • 2 changes


3h 17m • 2 changes


2h 54m • 2 changes


2h 54m • 2 changes


2h 54m • 2 changes
Want to know about travelling from Domodossola to Lyss? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct train from Domodossola to Lyss. However, there are services departing from Domodossola station and arriving at Lyss station via Spiez. The journey, including transfers, takes approximately 2h 54m.
Domodossola to Lyss train services, operated by BLS AG, depart from Domodossola station.
Domodossola to Lyss train services, operated by BLS AG, arrive at Bern station.
Book your Domodossola to Lyss train tickets online with BLS AG, Swiss Federal Railways (SBB CFF FFS) and Trenitalia EuroCity.
The distance between Domodossola and Lyss is 130.3 km. The road distance is 164 km.
You can take a train from Domodossola to Lyss via Spiez and Bern in around 2h 28m.