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Domodossola to Madrid trains

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Trip Overview

The average train between Domodossola and Madrid takes 27h 46m and the fastest train takes 24h 54m. The train runs, on average, 2 times per week from Domodossola to Madrid. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.

27h 46m
Duration
1,662 km
Distance
€330
Average price
Twice a week
Frequency

Domodossola to Madrid train times

Trains run twice a week between Domodossola and Madrid. The earliest departure is at 10:48 AM in the morning, and the last departure from Domodossola is at 9:48 PM which arrives into Madrid at 10:42 PM. All services require a transfer at Genève and take an average of 27h 46m. The schedules shown below are for the next available departures.

Departing Friday, October 16, 2026

  •  → 

    Arrives next day

    Trenitalia EuroCitySwiss Federal Railways (SBB CFF FFS)Société Nationale des Chemins de fer Français (SNCF)Renfe Viajerosiryo24h 54m • 4 changes

Departing Saturday, October 17, 2026

  •  → 

    Arrives next day

    Trenitalia EuroCitySwiss Federal Railways (SBB CFF FFS)Société Nationale des Chemins de fer Français (SNCF)TGV inOuiOuigo30h 38m • 4 changes

Frequently asked questions

Want to know about travelling from Domodossola to Madrid? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.

Map of how to get from Domodossola to Madrid.ExpandLaunch map view
  • Distance: 1,661.8 km
  • Duration: 27h 46m

What companies run services between Domodossola, Italy and Madrid, Spain?

You can take a train from Domodossola to Madrid-Puerta de Atocha-Almudena Grandes via Genève, Bellegarde, Lyon Part Dieu, and Barcelona-Sants in around 14h 52m.

Operators