The average train between Domodossola and Roma Termini takes 7h 24m and the fastest train takes 5h 59m. The train service runs several times per day from Domodossola to Roma Termini. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Trains run 5 times a day between Domodossola and Roma Termini. The earliest departure is at 6:06 AM in the morning, and the last departure from Domodossola is at 8:06 PM which arrives into Roma Termini at 9:19 AM. All services require a transfer at Milano P.Garibaldi and take an average of 7h 24m. The schedules shown below are for the next available departures.


6h 13m • 2 changes

5h 59m • 2 changes

6h 13m • 2 changes

6h 19m • 2 changes

6h 13m • 2 changes

6h 24m • 2 changes

6h 13m • 2 changes

6h 19m • 2 changesWant to know about travelling from Domodossola to Roma Termini? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct train from Domodossola to Roma Termini. However, there are services departing from Domodossola station and arriving at Roma Termini station via Milano P.Garibaldi station. The journey, including transfers, takes approximately 7h 24m.
Domodossola to Roma Termini train services, operated by Trenitalia, depart from Domodossola station.
Domodossola to Roma Termini train services, operated by ItaloTreno, arrive at Roma Termini station.
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The distance between Domodossola and Roma Termini is 576.9 km. The road distance is 697 km.
You can take a train from Domodossola to Roma Termini via Milano P.Garibaldi, Garibaldi Fs, Caiazzo, and Milano Centrale in around 5h 49m.