The average train between Dortmund and Neu-Isenburg takes 3h 25m and the fastest train takes 3h 15m. There is a train service every few hours from Dortmund to Neu-Isenburg. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Trains run every 2 hours between Dortmund and Neu-Isenburg. The earliest departure is at 6:36 AM in the morning, and the last departure from Dortmund is at 8:36 PM which arrives into Neu-Isenburg at 12:11 AM. All services require a transfer at Frankfurt and take an average of 3h 25m. The schedules shown below are for the next available departures.


3h 20m • 2 changes

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3h 15m • 2 changes

3h 15m • 2 changesWant to know about travelling from Dortmund to Neu-Isenburg? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct train from Dortmund to Neu-Isenburg. However, there are services departing from Dortmund station and arriving at Neu-Isenburg station via Frankfurt. The journey, including transfers, takes approximately 3h 25m.
Dortmund to Neu-Isenburg train services, operated by Deutsche Bahn Intercity (DB IC), depart from Dortmund Hbf station.
Dortmund to Neu-Isenburg train services, operated by Deutsche Bahn Intercity (DB IC), arrive at Frankfurt station.
Book your Dortmund to Neu-Isenburg train tickets online with Deutsche Bahn Intercity (DB IC), Verkehrsgesellschaft Frankfurt (VGF-FFM) and Nederlandse Spoorwegen (NS).
The distance between Dortmund and Neu-Isenburg is 184.5 km. The road distance is 277 km.
Deutsche Bahn Intercity (DB IC) operates a train from Dortmund Hbf to Frankfurt hourly. Tickets cost €45–100 and the journey takes 2h 13m.