The average train between Dortmund and Neu-Isenburg takes 3h 7m and the fastest train takes 2h 48m. The train service runs several times per day from Dortmund to Neu-Isenburg. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Trains run every 4 hours between Dortmund and Neu-Isenburg. The earliest departure is at 3:28 AM at night, and the last departure from Dortmund is at 7:35 PM which arrives into Neu-Isenburg at 11:41 PM. All services require a transfer at Frankfurt and take an average of 3h 7m. The schedules shown below are for the next available departures.

3h 42m • 1 change

2h 49m • 1 change

2h 48m • 1 change

2h 49m • 1 change

3h 42m • 1 change

2h 49m • 1 change

2h 48m • 1 change

2h 49m • 1 change

3h 43m • 1 change

2h 49m • 1 change

2h 48m • 1 change

2h 49m • 1 change

3h 5m • 1 change

2h 49m • 1 change

2h 48m • 1 change

2h 49m • 1 change

3h 5m • 1 change

2h 49m • 1 change

2h 48m • 1 change

2h 49m • 1 change

3h 5m • 1 change

2h 49m • 1 change

2h 48m • 1 change

2h 49m • 1 change
Want to know about travelling from Dortmund to Neu-Isenburg? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct train from Dortmund to Neu-Isenburg. However, there are services departing from Dortmund station and arriving at Neu-Isenburg station via Frankfurt. The journey, including transfers, takes approximately 3h 7m.
Dortmund to Neu-Isenburg train services, operated by Deutsche Bahn Intercity (DB IC), depart from Dortmund Hbf station.
Dortmund to Neu-Isenburg train services, operated by Deutsche Bahn Intercity (DB IC), arrive at Frankfurt station.
Book your Dortmund to Neu-Isenburg train tickets online with Deutsche Bahn Intercity (DB IC) and Verkehrsgesellschaft Frankfurt (VGF-FFM).
The distance between Dortmund and Neu-Isenburg is 184.5 km. The road distance is 276 km.
Deutsche Bahn Intercity (DB IC) operates a train from Dortmund Hbf to Frankfurt hourly. Tickets cost €45–210 and the journey takes 2h 13m. Nederlandse Spoorwegen (NS) also services this route once a week.