The average train between Downingtown and Syracuse takes 11h 4m and the fastest train takes 8h 12m. The train service runs several times per day from Downingtown to Syracuse. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Trains run 3 times a day between Downingtown and Syracuse. The earliest departure is at 7:47 AM in the morning, and the last departure from Downingtown is at 9:00 PM which arrives into Syracuse at 12:49 PM. All services require a transfer, and take on average 11h 4m. The schedules shown below are for the next available departures.

8h 16m • 1 change

9h 26m • 1 change
Arrives next day

16h 39m • 1 change

8h 12m • 1 change

8h 46m • 1 change
Arrives next day

15h 49m • 1 change

8h 12m • 1 change

8h 46m • 1 change
Arrives next day

15h 49m • 1 change

8h 12m • 1 change

8h 46m • 1 change
Arrives next day

15h 49m • 1 change
Want to know about travelling from Downingtown to Syracuse? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct train from Downingtown to Syracuse. However, there are services departing from Downingtown station and arriving at Syracuse station via Ny Moynihan Train Hall At Penn Station station. The journey, including transfers, takes approximately 11h 4m.
Downingtown to Syracuse train services, operated by Amtrak, depart from Downingtown Amtrak station.
Downingtown to Syracuse train services, operated by Amtrak, arrive at Syracuse Regional Transportation Center station.
Book your Downingtown to Syracuse train tickets online with Amtrak.
The distance between Downingtown and Syracuse is 340.2 km. The road distance is 663 km.
You can take a train from Downingtown Amtrak to Syracuse Regional Transportation Center via Ny Moynihan Train Hall At Penn Station in around 9h 3m.