The average train between Dresden Mitte Station and Prague takes 2h 29m and the fastest train takes 2h 15m. The train service runs several times per day from Dresden Mitte Station to Prague. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Trains run 3 times a day between Dresden Mitte Station and Prague. The earliest departure is at 8:42 AM in the morning, and the last departure from Dresden Mitte Station is at 10:03 PM which arrives into Prague at 12:58 AM. All services require a transfer, and take on average 2h 29m. The schedules shown below are for the next available departures.

2h 17m • 1 change

2h 17m • 1 change
Arrives next day

2h 17m • 1 change

2h 17m • 1 change
Arrives next day

2h 15m • 1 change

2h 17m • 1 change

2h 17m • 1 change
Arrives next day
Want to know about travelling from Dresden Mitte Station to Prague? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct train from Dresden Mitte Station to Prague. However, there are services departing from Dresden Mitte Station station and arriving at Prague station via Praha-Holesovice. The journey, including transfers, takes approximately 2h 29m.
Dresden Mitte Station to Prague train services, operated by Deutsche Bahn Regio (DB Regional), depart from Dresden Hbf station.
Dresden Mitte Station to Prague train services, operated by Deutsche Bahn Regio (DB Regional), arrive at Praha-Holesovice station.
The distance between Dresden Mitte Station and Prague is 118.4 km. The road distance is 187 km.
Danish Railways (DSB) operates a train from Dresden Hbf to Praha-Holesovice 5 times a day. Tickets cost Kč 850–1,400 and the journey takes 2h 5m. Le also services this route twice daily.