The average train between Duisburg and Mainz takes 2h 13m and the fastest train takes 1h 54m. There is an hourly train service from Duisburg to Mainz. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Trains run hourly between Duisburg and Mainz. The earliest departure is at 6:13 AM in the morning, and the last departure from Duisburg is at 11:35 PM which arrives into Mainz at 2:52 AM. All services require a transfer, and take on average 2h 13m. The schedules shown below are for the next available departures.

2h 9m • 1 change

1h 55m • 1 change

2h 15m • 1 change

2h 9m • 1 change

2h 9m • 1 change

1h 55m • 1 change

2h 15m • 1 change

2h 6m • 1 change

2h 9m • 1 change

1h 55m • 1 change

2h 15m • 1 change

2h 6m • 1 change
Want to know about travelling from Duisburg to Mainz? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct train from Duisburg to Mainz. However, there are services departing from Duisburg station and arriving at Mainz station via Frankfurt. The journey, including transfers, takes approximately 2h 13m.
Duisburg to Mainz train services, operated by Deutsche Bahn Intercity (DB IC), depart from Duisburg Hbf station.
Duisburg to Mainz train services, operated by Deutsche Bahn Intercity (DB IC), arrive at Frankfurt station.
Book your Duisburg to Mainz train tickets online with Deutsche Bahn Intercity (DB IC), Deutsche Bahn Regio (DB Regional) and 2 other operators.
The distance between Duisburg and Mainz is 193.1 km. The road distance is 256 km.
Deutsche Bahn Intercity (DB IC) operates a train from Duisburg Hbf to Frankfurt hourly. Tickets cost €40–180 and the journey takes 1h 34m. Nederlandse Spoorwegen (NS) also services this route hourly.