The average train between Duisburg and Mainz takes 2h 22m and the fastest train takes 2h 10m. There is a train service every few hours from Duisburg to Mainz. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Trains run hourly between Duisburg and Mainz. The earliest departure is at 4:44 AM at night, and the last departure from Duisburg is at 11:06 PM which arrives into Mainz at 2:52 AM. All services require a transfer at Frankfurt(M) Flughafen Fernbf and take an average of 2h 22m. The schedules shown below are for the next available departures.

2h 10m • 1 change
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2h 38m • 1 change
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2h 10m • 1 change
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2h 10m • 1 change
2h 39m • 1 change
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2h 10m • 1 changeWant to know about travelling from Duisburg to Mainz? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct train from Duisburg to Mainz. However, there are services departing from Duisburg station and arriving at Mainz station via Frankfurt(M) Flughafen Fernbf. The journey, including transfers, takes approximately 2h 22m.
Duisburg to Mainz train services, operated by Nederlandse Spoorwegen (NS), depart from Duisburg Hbf station.
Duisburg to Mainz train services, operated by Nederlandse Spoorwegen (NS), arrive at Frankfurt(M) Flughafen Fernbf station.
Book your Duisburg to Mainz train tickets online with Nederlandse Spoorwegen (NS), vlexx and 2 other operators.
The distance between Duisburg and Mainz is 193.1 km. The road distance is 258 km.
Nederlandse Spoorwegen (NS) operates a train from Duisburg Hbf to Frankfurt(M) Flughafen Fernbf hourly. Tickets cost €25–50 and the journey takes 1h 38m. Deutsche Bahn Intercity (DB IC) also services this route hourly.