The average train between Duisburg and Speyer takes 3h 7m and the fastest train takes 2h 42m. There is a train service every few hours from Duisburg to Speyer. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Trains run hourly between Duisburg and Speyer. The earliest departure is at 6:13 AM in the morning, and the last departure from Duisburg is at 11:15 PM which arrives into Speyer at 5:54 AM. All services require a transfer, and take on average 3h 7m. The schedules shown below are for the next available departures.

2h 43m • 1 change

2h 43m • 1 change

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2h 43m • 1 change

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2h 43m • 1 change

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2h 43m • 1 change

2h 43m • 1 change

2h 43m • 1 change

2h 43m • 1 change
Want to know about travelling from Duisburg to Speyer? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct train from Duisburg to Speyer. However, there are services departing from Duisburg station and arriving at Speyer station via Mannheim, Hauptbahnhof. The journey, including transfers, takes approximately 3h 7m.
Duisburg to Speyer train services, operated by Deutsche Bahn Intercity (DB IC), depart from Duisburg Hbf station.
Duisburg to Speyer train services, operated by Deutsche Bahn Intercity (DB IC), arrive at Mannheim, Hauptbahnhof station.
Book your Duisburg to Speyer train tickets online with Deutsche Bahn Intercity (DB IC), Deutsche Bahn Regio (DB Regional) and Nederlandse Spoorwegen (NS).
The distance between Duisburg and Speyer is 262.8 km. The road distance is 326 km.
Deutsche Bahn Intercity (DB IC) operates a train from Duisburg Hbf to Mannheim, Hauptbahnhof hourly. Tickets cost €55–240 and the journey takes 2h 13m. Nederlandse Spoorwegen (NS) also services this route 4 times a day.