The average train between Duomo (Milan Metro) (Station) and Rome takes 4h 6m and the fastest train takes 3h 22m. There is a train service every few hours from Duomo (Milan Metro) (Station) to Rome. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Trains run hourly between Duomo (Milan Metro) (Station) and Rome. The earliest departure is at 12:13 AM at night, and the last departure from Duomo (Milan Metro) (Station) is at 7:20 PM which arrives into Rome at 11:24 PM. All services require a transfer at Rho Fieramilano and take an average of 4h 6m. The schedules shown below are for the next available departures.

4h • 1 change

3h 58m • 1 change

3h 24m • 1 change

4h 3m • 1 change

8h 50m • 1 change

3h 29m • 1 change

3h 29m • 1 change

4h 3m • 1 change

8h 50m • 1 change

3h 28m • 1 change

3h 26m • 1 change

4h 6m • 1 change

9h 10m • 1 change

3h 33m • 1 change

3h 28m • 1 change

3h 58m • 1 change
Want to know about travelling from Duomo (Milan Metro) (Station) to Rome? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct train from Duomo (Milan Metro) (Station) to Rome. However, there are services departing from Duomo (Milan Metro) (Station) station and arriving at Rome station via Roma Termini. The journey, including transfers, takes approximately 4h 6m.
Duomo (Milan Metro) (Station) to Rome train services, operated by ATM, depart from Milano Rogoredo station.
Duomo (Milan Metro) (Station) to Rome train services, operated by ATM, arrive at Roma Termini station.
The distance between Duomo (Milan Metro) (Station) and Rome is 477.3 km. The road distance is 582 km.
ItaloTreno operates a train from Milano Rogoredo to Roma Termini every 30 minutes. Tickets cost €70–150 and the journey takes 2h 55m.