The average train between Durham and Isleworth takes 3h 48m and the fastest train takes 3h 28m. There is a train service every few hours from Durham to Isleworth. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Trains run hourly between Durham and Isleworth. The earliest departure is at 4:49 AM at night, and the last departure from Durham is at 10:11 PM which arrives into Isleworth at 6:20 AM. All services require a transfer at London Kings Cross and take an average of 3h 48m. The schedules shown below are for the next available departures.

3h 52m • 1 change

3h 28m • 1 change

3h 37m • 1 change

3h 37m • 1 change

3h 57m • 1 change

3h 38m • 1 change

3h 51m • 1 change

3h 52m • 1 change

3h 57m • 1 change

3h 38m • 1 change

3h 51m • 1 change

3h 52m • 1 change
Want to know about travelling from Durham to Isleworth? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct train from Durham to Isleworth. However, there are services departing from Durham station and arriving at Isleworth station via King's Cross. The journey, including transfers, takes approximately 3h 48m.
Durham to Isleworth train services, operated by London North Eastern Railway Limited (LNER), depart from Durham station.
Durham to Isleworth train services, operated by London North Eastern Railway Limited (LNER), arrive at King's Cross station.
Book your Durham to Isleworth train tickets online with London North Eastern Railway Limited (LNER) and London Underground (Tube).
The distance between Durham and Isleworth is 376.2 km. The road distance is 429 km.
London North Eastern Railway Limited (LNER) operates a train from Durham to King's Cross hourly. Tickets cost £85–120 and the journey takes 2h 50m.