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Durham to Cambridge trains

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Trip Overview

The average train between Durham and Cambridge takes 22h 42m and the fastest train takes 15h 17m. The train runs, on average, 6 times per week from Durham to Cambridge. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.

22h 42m
Duration
784 mi
Distance
$511
Average price
6 times a week
Frequency

Durham to Cambridge train times

Trains run 6 times a week between Durham and Cambridge. The service departs Durham at 9:27 AM in the morning, which arrives into Cambridge at 09:25:00. All services require a transfer, and take on average 22h 42m. The schedules shown below are for the next available departures.

Departing Thursday, November 5, 2026

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    Arrives next day

    AmtrakAmtrak Acela23h 58m • 1 change

Departing Friday, November 6, 2026

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    Arrives next day

    AmtrakAmtrak24h 31m • 1 change

Departing Saturday, November 7, 2026

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    Arrives next day

    AmtrakAmtrak24h 31m • 1 change

Departing Sunday, November 8, 2026

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    Arrives next day

    AmtrakAmtrak Acela15h 17m • 1 change

Departing Monday, November 9, 2026

  •  → 

    Arrives next day

    AmtrakAmtrak Acela23h 58m • 1 change

Departing Tuesday, November 10, 2026

  •  → 

    Arrives next day

    AmtrakAmtrak Acela23h 58m • 1 change

Frequently asked questions

Want to know about travelling from Durham to Cambridge? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.

Map of how to get from Durham to Cambridge.ExpandLaunch map view
  • Distance: 783.6 mi
  • Duration: 22h 42m

What companies run services between Durham, NC, USA and Cambridge, MA, USA?

You can take a train from Durham Amtrak Station to Boston via Ny Moynihan Train Hall At Penn Station in around 15h 25m.

Operators