The average train between East Saint Louis and Chicago takes 5h 27m and the fastest train takes 5h 18m. The train service runs several times per day from East Saint Louis to Chicago. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Trains run 5 times a day between East Saint Louis and Chicago. The earliest departure is at 4:05 AM at night, and the last departure from East Saint Louis is at 5:25 PM which arrives into Chicago at 10:43 PM. All services require a transfer at CIVIC CENTER station and take an average of 5h 27m. The schedules shown below are for the next available departures.

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Want to know about travelling from East Saint Louis to Chicago? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct train from East Saint Louis to Chicago. However, there are services departing from East Saint Louis station and arriving at Chicago station via Chicago Union Station station. The journey, including transfers, takes approximately 5h 27m.
East Saint Louis to Chicago train services, operated by Metro St. Louis, depart from St. Louis station.
East Saint Louis to Chicago train services, operated by Metro St. Louis, arrive at Chicago Union Station.
The distance between East Saint Louis and Chicago is 420.1 km. The road distance is 457 km.
Amtrak operates a train from St. Louis to Chicago Union Station 5 times a day. Tickets cost $90–190 and the journey takes 4h 55m.