The average train between Eisenach and Mainz takes 2h 47m and the fastest train takes 2h 30m. The train service runs several times per day from Eisenach to Mainz. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Trains run every 2 hours between Eisenach and Mainz. The earliest departure is at 12:11 AM at night, and the last departure from Eisenach is at 9:56 PM which arrives into Mainz at 12:52 AM. All services require a transfer, and take on average 2h 47m. The schedules shown below are for the next available departures.

2h 30m • 1 change

2h 48m • 1 change

2h 48m • 1 change
Arrives next day

2h 56m • 1 change

2h 41m • 1 change

2h 48m • 1 change

2h 48m • 1 change

2h 56m • 1 change

2h 48m • 1 change

2h 48m • 1 change

2h 56m • 1 change

2h 48m • 1 change

2h 41m • 1 change

2h 48m • 1 change

2h 48m • 1 change

2h 56m • 1 change

2h 41m • 1 change

2h 48m • 1 change

2h 48m • 1 change

2h 56m • 1 change

2h 41m • 1 change

2h 48m • 1 change

2h 48m • 1 change

2h 48m • 1 change
Want to know about travelling from Eisenach to Mainz? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct train from Eisenach to Mainz. However, there are services departing from Eisenach station and arriving at Mainz station via Frankfurt. The journey, including transfers, takes approximately 2h 47m.
Eisenach to Mainz train services, operated by Deutsche Bahn Intercity (DB IC), depart from Eisenach Hbf station.
Eisenach to Mainz train services, operated by Deutsche Bahn Intercity (DB IC), arrive at Mainz, Römisches Theater station.
Book your Eisenach to Mainz train tickets online with Deutsche Bahn Intercity (DB IC), vlexx and Deutsche Bahn Regio (DB Regional).
The distance between Eisenach and Mainz is 181.7 km. The road distance is 237 km.
You can take a train from Eisenach Hbf to Mainz, Römisches Theater via Frankfurt in around 2h 35m.