The average train between Enschede and Duisburg takes 3h 18m and the fastest train takes 2h 29m. There is a train service every few hours from Enschede to Duisburg. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Trains run hourly between Enschede and Duisburg. The earliest departure is at 5:56 AM in the morning, and the last departure from Enschede is at 9:03 PM which arrives into Duisburg at 6:59 AM. All services require a transfer at Duelmen and take an average of 3h 18m. The schedules shown below are for the next available departures.

3h 3m • 1 change

3h 3m • 1 change

2h 56m • 1 change

2h 56m • 1 change

2h 29m • 1 change

2h 29m • 1 change

2h 29m • 1 change

2h 29m • 1 change

2h 56m • 1 change

2h 56m • 1 change

2h 56m • 1 change

2h 56m • 1 change

3h 3m • 1 change

3h 3m • 1 change

2h 56m • 1 change

2h 56m • 1 change
Want to know about travelling from Enschede to Duisburg? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct train from Enschede to Duisburg. However, there are services departing from Enschede station and arriving at Duisburg station via Duelmen. The journey, including transfers, takes approximately 3h 18m.
Enschede to Duisburg train services, operated by Deutsche Bahn Regio (DB Regional), depart from Enschede station.
Enschede to Duisburg train services, operated by Deutsche Bahn Regio (DB Regional), arrive at Duisburg Hbf station.
Book your Enschede to Duisburg train tickets online with Deutsche Bahn Regio (DB Regional).
The distance between Enschede and Duisburg is 87.8 km. The road distance is 133 km.
You can take a train from Enschede to Duisburg Hbf via Duelmen and Dülmen, Bahnhof in around 2h 25m.