Esplanade de La Défense Station to Lyon Trains

Esplanade de La Défense Station to Lyon trains

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Trip Overview

The average train between Esplanade de La Défense Station and Lyon takes 2h 43m and the fastest train takes 2h 32m. There is a train service every few hours from Esplanade de La Défense Station to Lyon. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.

2h 43m
Duration: 442 km
Distance: €88
Average price: Hourly
Frequency

Train

best

Take the train from Paris Gare De Lyon to Lyon Perrachetrain Tgv

2h 50m

€53–153

Esplanade de La Défense Station to Lyon train times

Trains run hourly between Esplanade de La Défense Station and Lyon. The earliest departure is at 5:48 AM in the morning, and the last departure from Esplanade de La Défense Station is at 8:30 PM which arrives into Lyon at 11:24 PM. All services require a transfer at Gare de Lyon and take an average of 2h 43m. The schedules shown below are for the next available departures.

Departing Tuesday, August 25, 2026

6:34 AM → 9:10 AM
2h 35m • 1 change
8:32 AM → 11:10 AM
2h 37m • 1 change
9:02 AM → 11:49 AM
2h 46m • 1 change
9:34 AM → 12:10 PM
2h 35m • 1 change
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Departing Wednesday, August 26, 2026

5:48 AM → 8:34 AM
2h 45m • 1 change
6:34 AM → 9:10 AM
2h 35m • 1 change
8:32 AM → 11:10 AM
2h 37m • 1 change
9:02 AM → 11:49 AM
2h 46m • 1 change
Show more

Departing Thursday, August 27, 2026

5:48 AM → 8:34 AM
2h 45m • 1 change
6:34 AM → 9:10 AM
2h 35m • 1 change
8:32 AM → 11:10 AM
2h 37m • 1 change
9:02 AM → 11:49 AM
2h 46m • 1 change
Show more

Frequently asked questions

Want to know about travelling from Esplanade de La Défense Station to Lyon? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.

What companies run services between Esplanade de La Défense Station, France and Lyon, France?

TGV inOui operates a train from Paris Gare De Lyon to Lyon Perrache hourly. Tickets cost €85–140 and the journey takes 2h 10m. Two other operators also service this route.

Operators