The average train between Esslingen and Mainz takes 2h 19m and the fastest train takes 2h 13m. The train service runs several times per day from Esslingen to Mainz. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Trains run every 3 hours between Esslingen and Mainz. The earliest departure is at 6:09 AM in the morning, and the last departure from Esslingen is at 8:09 PM which arrives into Mainz at 10:22 PM. All services require a transfer, and take on average 2h 19m. The schedules shown below are for the next available departures.

2h 16m • 1 change

2h 14m • 1 change

2h 14m • 1 change

2h 14m • 1 change

2h 13m • 1 change

2h 13m • 1 change

2h 13m • 1 change

2h 13m • 1 change

2h 13m • 1 change

2h 13m • 1 change

2h 13m • 1 change

2h 13m • 1 change

2h 13m • 1 change

2h 13m • 1 change

2h 13m • 1 change

2h 13m • 1 change

2h 13m • 1 change

2h 13m • 1 change

2h 13m • 1 change

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2h 13m • 1 change

2h 13m • 1 change

2h 13m • 1 change

2h 13m • 1 change
Want to know about travelling from Esslingen to Mainz? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct train from Esslingen to Mainz. However, there are services departing from Esslingen station and arriving at Mainz station via Frankfurt. The journey, including transfers, takes approximately 2h 19m.
Esslingen to Mainz train services, operated by Deutsche Bahn Intercity (DB IC), depart from Esslingen station.
Esslingen to Mainz train services, operated by Deutsche Bahn Intercity (DB IC), arrive at Frankfurt station.
Book your Esslingen to Mainz train tickets online with Deutsche Bahn Intercity (DB IC) and Deutsche Bahn Regio (DB Regional).
The distance between Esslingen and Mainz is 157.1 km. The road distance is 212 km.
Deutsche Bahn Intercity (DB IC) operates a train from Esslingen to Frankfurt hourly. Tickets cost €30–150 and the journey takes 1h 29m.