The average train between Firenze Santa Maria Novella and Roma Ostiense takes 1h 57m and the fastest train takes 1h 46m. There is a train service every few hours from Firenze Santa Maria Novella to Roma Ostiense. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Trains run hourly between Firenze Santa Maria Novella and Roma Ostiense. The earliest departure is at 8:43 AM in the morning, and the last departure from Firenze Santa Maria Novella is at 8:28 PM which arrives into Roma Ostiense at 10:14 PM. All services require a transfer, and take on average 1h 57m. The schedules shown below are for the next available departures.

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Want to know about travelling from Firenze Santa Maria Novella to Roma Ostiense? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct train from Firenze Santa Maria Novella to Roma Ostiense. However, there are services departing from Firenze Santa Maria Novella station and arriving at Roma Ostiense station via Roma Tiburtina. The journey, including transfers, takes approximately 1h 57m.
Firenze Santa Maria Novella to Roma Ostiense train services, operated by ItaloTreno, depart from Firenze Santa Maria Novella station.
Firenze Santa Maria Novella to Roma Ostiense train services, operated by ItaloTreno, arrive at Roma Tiburtina station.
Book your Firenze Santa Maria Novella to Roma Ostiense train tickets online with ItaloTreno and Trenitalia.
The distance between Firenze Santa Maria Novella and Roma Ostiense is 235.4 km. The road distance is 264 km.
ItaloTreno operates a train from Firenze Santa Maria Novella to Roma Tiburtina hourly. Tickets cost €30–65 and the journey takes 1h 48m.