The average train between Fiumicino and Isernia takes 2h 53m and the fastest train takes 2h 45m. The train service runs several times per day from Fiumicino to Isernia. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Trains run 5 times a day between Fiumicino and Isernia. The earliest departure is at 5:38 AM in the morning, and the last departure from Fiumicino is at 7:38 PM which arrives into Isernia at 10:23 PM. All services require a transfer, and take on average 2h 53m. The schedules shown below are for the next available departures.

2h 49m • 1 change

2h 52m • 1 change

3h • 1 change

2h 47m • 1 change

2h 49m • 1 change

2h 52m • 1 change

3h • 1 change

2h 47m • 1 change

2h 49m • 1 change

2h 52m • 1 change

3h • 1 change

2h 47m • 1 change

2h 49m • 1 change

2h 52m • 1 change

3h • 1 change

2h 47m • 1 change

2h 49m • 1 change

2h 52m • 1 change

2h 47m • 1 change

3h 2m • 1 change

2h 49m • 1 change

2h 52m • 1 change

3h • 1 change

2h 47m • 1 change
Want to know about travelling from Fiumicino to Isernia? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct train from Fiumicino to Isernia. However, there are services departing from Fiumicino station and arriving at Isernia station via Isernia. The journey, including transfers, takes approximately 2h 53m.
Fiumicino to Isernia train services, operated by Trenitalia, depart from Roma Termini station.
Fiumicino to Isernia train services, operated by Trenitalia, arrive at Isernia station.
Book your Fiumicino to Isernia train tickets online with Trenitalia.
The distance between Fiumicino and Isernia is 167 km. The road distance is 218 km.
Trenitalia operates a train from Roma Termini to Isernia every 3 hours. Tickets cost €23–40 and the journey takes 2h 16m.