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Florence to Cuenca trains

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Trip Overview

The average train between Florence and Cuenca takes 40h 38m and the fastest train takes 40h 14m. The train runs, on average, 5 times per week from Florence to Cuenca. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.

40h 38m
Duration
2,199 km
Distance
€333
Average price
5 times a week
Frequency

Florence to Cuenca train times

Trains run 5 times a week between Florence and Cuenca. The service departs Florence at 6:25 PM in the evening, which arrives into Cuenca at 10:39:00. All services require a transfer at Milano Centrale and take an average of 40h 38m. The schedules shown below are for the next available departures.

Departing Wednesday, October 21, 2026

  •  → 

    Arrives +2 days

    ItaloTrenoTrenitaliaRenfe ViajerosiryoRenfe AVE40h 14m • 4 changes

Departing Thursday, October 22, 2026

  •  → 

    Arrives +2 days

    ItaloTrenoTrenitaliaRenfe ViajerosRenfe AVERenfe AVE40h 14m • 4 changes

Departing Friday, October 23, 2026

  •  → 

    Arrives +2 days

    ItaloTrenoTrenitaliaRenfe ViajerosRenfe AVERenfe AVE41h 14m • 4 changes

Departing Saturday, October 24, 2026

  •  → 

    Arrives +2 days

    ItaloTrenoTrenitaliaRenfe ViajerosRenfe AVERenfe AVE41h 14m • 4 changes

Departing Sunday, October 25, 2026

  •  → 

    Arrives +2 days

    ItaloTrenoTrenitaliaRenfe ViajerosRenfe AVERenfe AVE40h 14m • 4 changes

Frequently asked questions

Want to know about travelling from Florence to Cuenca? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.

Map of how to get from Florence to Cuenca.ExpandLaunch map view
  • Distance: 2,199 km
  • Duration: 40h 38m

What companies run services between Florence, Italy and Cuenca, Spain?

You can take a train from Firenze Santa Maria Novella to Cuenca Fernando Zobel via Milano Centrale, Lyon Part Dieu, Barcelona-Sants, and Madrid-Puerta de Atocha-Almudena Grandes in around 18h 17m.

Operators