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Florence to Enschede trains

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Trip Overview

The average train between Florence and Enschede takes 20h 2m and the fastest train takes 15h 2m. The train service runs several times per day from Florence to Enschede. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.

20h 2m
Duration
1,375 km
Distance
€271
Average price
Twice daily
Frequency

Florence to Enschede train times

Trains run twice daily between Florence and Enschede. The earliest departure is at 7:25 AM in the morning, and the last departure from Florence is at 9:25 PM which arrives into Enschede at 8:27 PM. All services require a transfer at Milano Centrale and take an average of 20h 2m. The schedules shown below are for the next available departures.

Departing Monday, November 9, 2026

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    Arrives next day

    ItaloTrenoTrenitalia EuroCityDeutsche Bahn Intercity (DB IC)Deutsche Bahn Regio (DB Regional)21h 2m • 3 changes
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    Arrives next day

    ItaloTrenoTrenitalia EuroCityDeutsche Bahn Intercity (DB IC)Deutsche Bahn Regio (DB Regional)23h 2m • 3 changes

Departing Tuesday, November 10, 2026

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    ItaloTrenoTrenitalia EuroCityDeutsche Bahn Intercity (DB IC)Deutsche Bahn Regio (DB Regional)15h 2m • 3 changes
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    Arrives next day

    ItaloTrenoTrenitalia EuroCityDeutsche Bahn Intercity (DB IC)Deutsche Bahn Regio (DB Regional)21h 2m • 3 changes
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    Arrives next day

    ItaloTrenoTrenitalia EuroCityDeutsche Bahn Intercity (DB IC)Deutsche Bahn Regio (DB Regional)23h 2m • 3 changes

Departing Wednesday, November 11, 2026

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    ItaloTrenoTrenitalia EuroCityDeutsche Bahn Intercity (DB IC)Deutsche Bahn Regio (DB Regional)15h 2m • 3 changes
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    Arrives next day

    ItaloTrenoTrenitalia EuroCityDeutsche Bahn Intercity (DB IC)Deutsche Bahn Regio (DB Regional)21h 2m • 3 changes
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    Arrives next day

    ItaloTrenoTrenitalia EuroCityDeutsche Bahn Intercity (DB IC)Deutsche Bahn Regio (DB Regional)23h 2m • 3 changes

Departing Thursday, November 12, 2026

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    ItaloTrenoTrenitalia EuroCityDeutsche Bahn Intercity (DB IC)Deutsche Bahn Regio (DB Regional)15h 2m • 3 changes
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    Arrives next day

    ItaloTrenoTrenitalia EuroCityDeutsche Bahn Intercity (DB IC)Deutsche Bahn Regio (DB Regional)21h 2m • 3 changes
  •  → 

    Arrives next day

    ItaloTrenoTrenitalia EuroCityDeutsche Bahn Intercity (DB IC)Deutsche Bahn Regio (DB Regional)23h 2m • 3 changes

Departing Friday, November 13, 2026

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    ItaloTrenoTrenitalia EuroCityDeutsche Bahn Intercity (DB IC)Deutsche Bahn Regio (DB Regional)15h 2m • 3 changes
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    Arrives next day

    ItaloTrenoTrenitalia EuroCityDeutsche Bahn Intercity (DB IC)Deutsche Bahn Regio (DB Regional)21h 2m • 3 changes

Departing Saturday, November 14, 2026

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    Arrives next day

    ItaloTrenoTrenitalia EuroCityDeutsche Bahn Intercity (DB IC)Deutsche Bahn Regio (DB Regional)28h 2m • 3 changes

Frequently asked questions

Want to know about travelling from Florence to Enschede? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.

Map of how to get from Florence to Enschede.ExpandLaunch map view
  • Distance: 1,375 km
  • Duration: 20h 2m

What companies run services between Florence, Italy and Enschede, Netherlands?

You can take a train from Firenze Santa Maria Novella to Enschede via Milano Centrale, Basel SBB, and Münster Hauptbahnhof in around 15h 42m.

Operators