The average train between Florence and Enschede takes 21h 34m and the fastest train takes 15h 2m. The train service runs several times per day from Florence to Enschede. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Trains run twice daily between Florence and Enschede. The earliest departure is at 7:25 AM in the morning, and the last departure from Florence is at 6:25 PM which arrives into Enschede at 8:27 PM. All services require a transfer at Milano Centrale and take an average of 21h 34m. The schedules shown below are for the next available departures.
Arrives next day



30h 2m • 3 changesArrives next day



26h 2m • 3 changes


15h 2m • 3 changesArrives next day



22h 2m • 3 changesArrives next day



26h 2m • 3 changes


15h 2m • 3 changesArrives next day



22h 2m • 3 changesArrives next day



26h 2m • 3 changes


15h 2m • 3 changesArrives next day



22h 2m • 3 changesArrives next day



26h 2m • 3 changesWant to know about travelling from Florence to Enschede? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct train from Florence to Enschede. However, there are services departing from Florence station and arriving at Enschede station via Milano Centrale. The journey, including transfers, takes approximately 21h 34m.
Florence to Enschede train services, operated by ItaloTreno, depart from Firenze Santa Maria Novella station.
Florence to Enschede train services, operated by ItaloTreno, arrive at Enschede station.
Book your Florence to Enschede train tickets online with ItaloTreno, Trenitalia EuroCity and 2 other operators.
The distance between Florence and Enschede is 992.2 km. The road distance is 1,394 km.
You can take a train from Firenze Santa Maria Novella to Enschede via Milano Centrale, Basel SBB, and Münster Hauptbahnhof in around 15h 41m.