The average train between Florence and Isernia takes 6h 56m and the fastest train takes 4h 24m. There is at least one train per day from Florence to Isernia. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Trains run once daily between Florence and Isernia. The earliest departure is at 3:28 PM in the afternoon, and the last departure from Florence is at 8:43 PM which arrives into Isernia at 11:15 AM. All services require a transfer, and take on average 6h 56m. The schedules shown below are for the next available departures.
Want to know about travelling from Florence to Isernia? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct train from Florence to Isernia. However, there are services departing from Florence station and arriving at Isernia station via Roma Tiburtina. The journey, including transfers, takes approximately 6h 56m.
Florence to Isernia train services, operated by ItaloTreno, depart from Firenze Santa Maria Novella station.
Florence to Isernia train services, operated by ItaloTreno, arrive at Isernia station.
Book your Florence to Isernia train tickets online with ItaloTreno and Trenitalia.
The distance between Florence and Isernia is 344.3 km. The road distance is 441 km.
You can take a train from Firenze Santa Maria Novella to Isernia via Roma Tiburtina in around 4h 40m.
