Florence to Sant'Antimo Trains

Trip Overview

The average train between Florence and Sant'Antimo takes 3h 56m and the fastest train takes 3h 21m. There is a train service every few hours from Florence to Sant'Antimo. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.

3h 56m
Duration: 498 km
Distance: €81
Average price: Hourly
Frequency

Train

best

Take the train from Firenze S.M.N. to Napoli Centraletrain Fr

3h 33m

€58–114

Florence to Sant'Antimo train times

Trains run hourly between Florence and Sant'Antimo. The earliest departure is at 6:00 AM in the morning, and the last departure from Florence is at 8:48 PM which arrives into Sant'Antimo at 4:22 AM. All services require a transfer, and take on average 3h 56m. The schedules shown below are for the next available departures.

Departing Monday, November 9, 2026

9:48 AM → 1:24 PM
3h 36m • 1 change
10:14 AM → 2:03 PM
3h 49m • 1 change
11:14 AM → 3:00 PM
3h 46m • 1 change
12:14 PM → 4:00 PM
3h 46m • 1 change
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Departing Tuesday, November 10, 2026

6:00 AM → 10:00 AM
4h • 1 change
7:14 AM → 11:16 AM
4h 2m • 1 change
8:48 AM → 12:13 PM
3h 25m • 1 change
9:14 AM → 1:00 PM
3h 46m • 1 change
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Departing Wednesday, November 11, 2026

6:00 AM → 10:00 AM
4h • 1 change
7:14 AM → 11:16 AM
4h 2m • 1 change
8:48 AM → 12:13 PM
3h 25m • 1 change
9:14 AM → 1:00 PM
3h 46m • 1 change
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Departing Thursday, November 12, 2026

6:00 AM → 10:00 AM
4h • 1 change
7:14 AM → 11:16 AM
4h 2m • 1 change
8:48 AM → 12:13 PM
3h 25m • 1 change
9:14 AM → 1:00 PM
3h 46m • 1 change
Show more

Departing Friday, November 13, 2026

6:00 AM → 10:00 AM
4h • 1 change
7:14 AM → 11:16 AM
4h 2m • 1 change
8:48 AM → 12:13 PM
3h 25m • 1 change
9:14 AM → 1:00 PM
3h 46m • 1 change
Show more

Departing Saturday, November 14, 2026

6:00 AM → 10:00 AM
4h • 1 change
8:48 AM → 12:13 PM
3h 25m • 1 change
9:14 AM → 1:00 PM
3h 46m • 1 change
9:48 AM → 1:23 PM
3h 35m • 1 change
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Departing Sunday, November 15, 2026

7:14 AM → 11:36 AM
4h 22m • 1 change
10:14 AM → 2:23 PM
4h 9m • 1 change
11:14 AM → 2:53 PM
3h 39m • 1 change
12:48 PM → 4:36 PM
3h 48m • 1 change
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Frequently asked questions

Want to know about travelling from Florence to Sant'Antimo? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.