The average train between Florence and Santa Maria Maggiore takes 9h 52m and the fastest train takes 5h 23m. The train service runs several times per day from Florence to Santa Maria Maggiore. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Trains run 4 times a day between Florence and Santa Maria Maggiore. The earliest departure is at 8:25 AM in the morning, and the last departure from Florence is at 6:25 PM which arrives into Santa Maria Maggiore at 10:11 AM. All services require a transfer at Milano Centrale and take an average of 9h 52m. The schedules shown below are for the next available departures.


5h 46m • 2 changes

5h 46m • 2 changes

5h 46m • 2 changes

5h 23m • 2 changes

5h 46m • 2 changes

5h 46m • 2 changes

5h 46m • 2 changes

5h 23m • 2 changesWant to know about travelling from Florence to Santa Maria Maggiore? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct train from Florence to Santa Maria Maggiore. However, there are services departing from Firenze Santa Maria Novella station and arriving at Domodossola station via Milano Centrale station. The journey, including transfers, takes approximately 9h 52m.
Florence to Santa Maria Maggiore train services, operated by ItaloTreno, depart from Firenze Santa Maria Novella station.
Florence to Santa Maria Maggiore train services, operated by Trenitalia EuroCity, arrive at Domodossola station.
The distance between Florence and Santa Maria Maggiore is 341.2 km. The road distance is 439 km.
You can take a train from Firenze Santa Maria Novella to S. Maria Maggiore via Milano Centrale and Domodossola in around 5h 49m.