The train between Florence and Seregno takes 2h 36m. There is a train service every few hours from Florence to Seregno. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Trains run every 2 hours between Florence and Seregno. The earliest departure is at 7:25 AM in the morning, and the last departure from Florence is at 7:25 PM which arrives into Seregno at 10:01 PM. All services require a transfer, and take on average 2h 36m. The schedules shown below are for the next available departures.

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2h 36m • 1 changeWant to know about travelling from Florence to Seregno? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct train from Florence to Seregno. However, there are services departing from Florence station and arriving at Seregno station via Milano Centrale. The journey, including transfers, takes approximately 2h 36m.
Florence to Seregno train services, operated by ItaloTreno, depart from Firenze Santa Maria Novella station.
Florence to Seregno train services, operated by ItaloTreno, arrive at Milano Centrale station.
Book your Florence to Seregno train tickets online with ItaloTreno and Swiss Federal Railways (SBB CFF FFS).
The distance between Florence and Seregno is 263.2 km. The road distance is 325 km.
ItaloTreno operates a train from Firenze Santa Maria Novella to Milano Centrale every 2 hours. Tickets cost €35–60 and the journey takes 1h 55m.