The average train between Florence and Seregno takes 3h 24m and the fastest train takes 3h 6m. There is a train service every few hours from Florence to Seregno. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Trains run hourly between Florence and Seregno. The earliest departure is at 6:55 AM in the morning, and the last departure from Florence is at 9:55 PM which arrives into Seregno at 6:01 AM. All services require a transfer, and take on average 3h 24m. The schedules shown below are for the next available departures.

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Want to know about travelling from Florence to Seregno? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct train from Florence to Seregno. However, there are services departing from Florence station and arriving at Seregno station via Milano Centrale. The journey, including transfers, takes approximately 3h 24m.
Florence to Seregno train services, operated by Trenitalia Frecce, depart from Firenze S.M.N. station.
Florence to Seregno train services, operated by Trenitalia Frecce, arrive at Milano Centrale station.
Book your Florence to Seregno train tickets online with Trenitalia Frecce and Swiss Federal Railways (SBB CFF FFS).
The distance between Florence and Seregno is 263.2 km. The road distance is 326 km.
Trenitalia Frecce operates a train from Firenze S.M.N. to Milano Centrale hourly. Tickets cost €45–90 and the journey takes 1h 56m. Two other operators also service this route.