The average train between Florence and Seregno takes 3h and the fastest train takes 2h 36m. There is a train service every few hours from Florence to Seregno. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Trains run hourly between Florence and Seregno. The earliest departure is at 7:25 AM in the morning, and the last departure from Florence is at 9:25 PM which arrives into Seregno at 6:01 AM. All services require a transfer, and take on average 3h. The schedules shown below are for the next available departures.

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2h 36m • 1 changeWant to know about travelling from Florence to Seregno? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct train from Florence to Seregno. However, there are services departing from Firenze Santa Maria Novella station and arriving at Milano Centrale station via Milano Centrale station. The journey, including transfers, takes approximately 3h.
Florence to Seregno train services, operated by ItaloTreno, depart from Firenze Santa Maria Novella station.
Florence to Seregno train services, operated by ItaloTreno, arrive at Milano Centrale station.
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The distance between Florence and Seregno is 263.2 km. The road distance is 320 km.
ItaloTreno operates a train from Firenze Santa Maria Novella to Milano Centrale hourly. Tickets cost €35–65 and the journey takes 1h 55m.