The average train between Florence and Termoli takes 4h 57m and the fastest train takes 4h 55m. The train service runs several times per day from Florence to Termoli. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Trains run every 3 hours between Florence and Termoli. The earliest departure is at 7:39 AM in the morning, and the last departure from Florence is at 4:39 PM which arrives into Termoli at 9:43 PM. All services require a transfer, and take on average 4h 57m. The schedules shown below are for the next available departures.

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4h 55m • 1 changeWant to know about travelling from Florence to Termoli? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct train from Florence to Termoli. However, there are services departing from Firenze Santa Maria Novella station and arriving at Termoli station via Bologna centrale station. The journey, including transfers, takes approximately 4h 57m.
Florence to Termoli train services, operated by ItaloTreno, depart from Firenze Santa Maria Novella station.
Florence to Termoli train services, operated by Trenitalia Frecce, arrive at Termoli station.
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The distance between Florence and Termoli is 363.8 km. The road distance is 503 km.
You can take a train from Firenze Santa Maria Novella to Termoli via Bologna Centrale in around 5h 15m.