Rome2Rio

Florence to Buffalo trains

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Trip Overview

The average train between Florence and Buffalo takes 26h 6m and the fastest train takes 23h 10m. The train service runs several times per day from Florence to Buffalo. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.

26h 6m
Duration
1,070 mi
Distance
$689
Average price
Twice daily
Frequency

Florence to Buffalo train times

Trains run twice daily between Florence and Buffalo. The earliest departure is at 10:54 AM in the morning, and the last departure from Florence is at 10:32 PM which arrives into Buffalo at 9:42 PM. All services require a transfer, and take on average 26h 6m. The schedules shown below are for the next available departures.

Departing Thursday, November 12, 2026

  •  → 

    Arrives next day

    AmtrakAmtrak28h 38m • 1 change
  •  → 

    Arrives next day

    AmtrakAmtrak23h 10m • 1 change

Departing Friday, November 13, 2026

  •  → 

    Arrives next day

    AmtrakAmtrak28h 38m • 1 change
  •  → 

    Arrives next day

    AmtrakAmtrak23h 10m • 1 change

Departing Saturday, November 14, 2026

  •  → 

    Arrives next day

    AmtrakAmtrak28h 38m • 1 change
  •  → 

    Arrives next day

    AmtrakAmtrak23h 10m • 1 change

Departing Sunday, November 15, 2026

  •  → 

    Arrives next day

    AmtrakAmtrak28h 38m • 1 change
  •  → 

    Arrives next day

    AmtrakAmtrak23h 10m • 1 change

Departing Monday, November 16, 2026

  •  → 

    Arrives next day

    AmtrakAmtrak28h 38m • 1 change
  •  → 

    Arrives next day

    AmtrakAmtrak23h 10m • 1 change

Departing Tuesday, November 17, 2026

  •  → 

    Arrives next day

    AmtrakAmtrak28h 38m • 1 change
  •  → 

    Arrives next day

    AmtrakAmtrak23h 10m • 1 change

Frequently asked questions

Want to know about travelling from Florence to Buffalo? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.

Map of how to get from Florence to Buffalo.ExpandLaunch map view
  • Distance: 1,069.9 mi
  • Duration: 26h 6m

What companies run services between Florence, SC, USA and Buffalo, NY, USA?

You can take a train from Florence Station to Buffalo via Ny Moynihan Train Hall At Penn Station in around 22h 4m.

Operators