The average train between Florence and St. Louis takes 43h 15m and the fastest train takes 41h 19m. The train runs, on average, 6 times per week from Florence to St. Louis. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Trains run 6 times a week between Florence and St. Louis. The earliest departure is at 10:32 PM at night, and the last departure from Florence is at 10:32 PM which arrives into St. Louis at 2:51 PM. All services require a transfer at Petersburg Amtrak Station and take an average of 43h 15m. The schedules shown below are for the next available departures.
Want to know about travelling from Florence to St. Louis? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct train from Florence to St. Louis. However, there are services departing from Florence station and arriving at St. Louis station via Petersburg Amtrak Station station. The journey, including transfers, takes approximately 43h 15m.
Florence to St. Louis train services, operated by Amtrak, depart from Florence Station.
Florence to St. Louis train services, operated by Amtrak, arrive at St. Louis station.
Book your Florence to St. Louis train tickets online with Amtrak.
The distance between Florence and St. Louis is 1,054.9 km. The road distance is 2,343 km.
You can take a train from Florence Station to St. Louis via Petersburg Amtrak Station and Chicago Union Station in around 33h 14m.