The average train between Framingham and Midtown Manhattan takes 5h 36m and the fastest train takes 4h 35m. There is a train service every few hours from Framingham to Midtown Manhattan. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Trains run hourly between Framingham and Midtown Manhattan. The earliest departure is at 12:03 AM at night, and the last departure from Framingham is at 11:29 PM which arrives into Midtown Manhattan at 8:51 AM. All services require a transfer at Back Bay and take an average of 5h 36m. The schedules shown below are for the next available departures.

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5h 8m • 1 change
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4h 47m • 1 changeWant to know about travelling from Framingham to Midtown Manhattan? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct train from Framingham to Midtown Manhattan. However, there are services departing from Boston station and arriving at Ny Moynihan Train Hall At Penn Station via Ny Moynihan Train Hall At Penn Station. The journey, including transfers, takes approximately 5h 36m.
Framingham to Midtown Manhattan train services, operated by Amtrak, depart from Boston station.
Framingham to Midtown Manhattan train services, operated by Amtrak, arrive at Ny Moynihan Train Hall At Penn Station.
The distance between Framingham and Midtown Manhattan is 272 km. The road distance is 305 km.
Amtrak operates a train from Boston to Ny Moynihan Train Hall At Penn Station every 3 hours. Tickets cost $120–200 and the journey takes 3h 57m. Amtrak Acela also services this route every 4 hours.