The average train between Frankfurt(Main)Hbf and Melsungen takes 2h 25m and the fastest train takes 2h 5m. There is an hourly train service from Frankfurt(Main)Hbf to Melsungen. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Trains run hourly between Frankfurt(Main)Hbf and Melsungen. The earliest departure is at 4:21 AM at night, and the last departure from Frankfurt(Main)Hbf is at 11:20 PM which arrives into Melsungen at 4:17 AM. All services require a transfer, and take on average 2h 25m. The schedules shown below are for the next available departures.

2h 18m • 1 change

2h 47m • 1 change

2h 6m • 1 change
Arrives next day

3h 13m • 1 change

2h 13m • 1 change

2h 47m • 1 change

2h 18m • 1 change

2h 19m • 1 change

3h 12m • 1 change

2h 47m • 1 change

2h 18m • 1 change

2h 19m • 1 change
Want to know about travelling from Frankfurt(Main)Hbf to Melsungen? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct train from Frankfurt(Main)Hbf to Melsungen. However, there are services departing from Frankfurt(Main)Hbf station and arriving at Melsungen station via Kassel Bahnhof Wilhelmshöhe. The journey, including transfers, takes approximately 2h 25m.
Frankfurt(Main)Hbf to Melsungen train services, operated by Deutsche Bahn Intercity (DB IC), depart from Frankfurt station.
Frankfurt(Main)Hbf to Melsungen train services, operated by Deutsche Bahn Intercity (DB IC), arrive at Kassel Bahnhof Wilhelmshöhe station.
The distance between Frankfurt(Main)Hbf and Melsungen is 129.7 km. The road distance is 217 km.
Deutsche Bahn Intercity (DB IC) operates a train from Frankfurt to Kassel Bahnhof Wilhelmshöhe hourly. Tickets cost €35–150 and the journey takes 1h 25m. Deutsche Bahn Regio (DB Regional) also services this route every 3 hours.