The average train between Frankfurt(Main)Hbf and Prague takes 8h 17m and the fastest train takes 7h 19m. The train service runs several times per day from Frankfurt(Main)Hbf to Prague. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Trains run every 4 hours between Frankfurt(Main)Hbf and Prague. The earliest departure is at 4:54 AM at night, and the last departure from Frankfurt(Main)Hbf is at 8:57 PM which arrives into Prague at 10:21 AM. All services require a transfer at Nürnberg Hbf and take an average of 8h 17m. The schedules shown below are for the next available departures.


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Want to know about travelling from Frankfurt(Main)Hbf to Prague? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct train from Frankfurt(Main)Hbf to Prague. However, there are services departing from Frankfurt(Main)Hbf station and arriving at Prague station via Nürnberg Hbf. The journey, including transfers, takes approximately 8h 17m.
Frankfurt(Main)Hbf to Prague train services, operated by Deutsche Bahn Intercity (DB IC), depart from Frankfurt station.
Frankfurt(Main)Hbf to Prague train services, operated by Deutsche Bahn Intercity (DB IC), arrive at Praha Hlavni Nadrazi station.
Book your Frankfurt(Main)Hbf to Prague train tickets online with Deutsche Bahn Intercity (DB IC), Deutsche Bahn Regio (DB Regional) and Die Länderbahn.
The distance between Frankfurt(Main)Hbf and Prague is 410.5 km. The road distance is 564 km.
You can take a train from Frankfurt to Praha Hlavni Nadrazi via Nürnberg Hbf and Schwandorf in around 8h 9m.