The average train between Frankfurt am Main and Duffel takes 4h 6m and the fastest train takes 3h 56m. The train service runs several times per day from Frankfurt am Main to Duffel. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Trains run every 3 hours between Frankfurt am Main and Duffel. The earliest departure is at 6:34 AM in the morning, and the last departure from Frankfurt am Main is at 8:14 PM which arrives into Duffel at 12:30 AM. All services require a transfer, and take on average 4h 6m. The schedules shown below are for the next available departures.

4h 4m • 1 change

4h 5m • 1 change
Arrives next day

4h 24m • 1 change

3h 56m • 1 change

3h 57m • 1 change

3h 56m • 1 change

3h 56m • 1 change

3h 56m • 1 change

3h 57m • 1 change

3h 56m • 1 change

3h 56m • 1 change

3h 56m • 1 change

3h 57m • 1 change

3h 56m • 1 change

3h 56m • 1 change

3h 56m • 1 change

3h 57m • 1 change

3h 56m • 1 change

3h 56m • 1 change

3h 56m • 1 change

3h 57m • 1 change

3h 56m • 1 change

3h 56m • 1 change

3h 58m • 1 change

3h 59m • 1 change

3h 58m • 1 change

3h 58m • 1 change
Want to know about travelling from Frankfurt am Main to Duffel? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct train from Frankfurt am Main to Duffel. However, there are services departing from Frankfurt am Main station and arriving at Duffel station via Brussels-Nord. The journey, including transfers, takes approximately 4h 6m.
Frankfurt am Main to Duffel train services, operated by Deutsche Bahn Intercity (DB IC), depart from Frankfurt station.
Frankfurt am Main to Duffel train services, operated by Deutsche Bahn Intercity (DB IC), arrive at Brussels-Nord station.
Book your Frankfurt am Main to Duffel train tickets online with Deutsche Bahn Intercity (DB IC) and Belgian Railways (NMBS/SNCB).
The distance between Frankfurt am Main and Duffel is 314.1 km. The road distance is 424 km.
Deutsche Bahn Intercity (DB IC) operates a train from Frankfurt to Brussels-Nord every 4 hours. Tickets cost €70–310 and the journey takes 3h 10m.