The average train between Frankfurt am Main and Enschede takes 5h 32m and the fastest train takes 4h 49m. The train service runs several times per day from Frankfurt am Main to Enschede. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Trains run every 4 hours between Frankfurt am Main and Enschede. The earliest departure is at 4:46 AM at night, and the last departure from Frankfurt am Main is at 9:08 PM which arrives into Enschede at 8:57 AM. All services require a transfer at Essen Hbf and take an average of 5h 32m. The schedules shown below are for the next available departures.


4h 49m • 2 changes


4h 49m • 2 changes
Arrives next day


12h 49m • 2 changes


5h 11m • 2 changes


5h 16m • 2 changes


4h 49m • 2 changes


4h 49m • 2 changes


5h 11m • 2 changes


5h 16m • 2 changes


4h 49m • 2 changes


4h 49m • 2 changes
Want to know about travelling from Frankfurt am Main to Enschede? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct train from Frankfurt am Main to Enschede. However, there are services departing from Frankfurt am Main station and arriving at Enschede station via Essen Hbf. The journey, including transfers, takes approximately 5h 32m.
Frankfurt am Main to Enschede train services, operated by Deutsche Bahn Intercity (DB IC), depart from Frankfurt station.
Frankfurt am Main to Enschede train services, operated by Deutsche Bahn Intercity (DB IC), arrive at Enschede station.
Book your Frankfurt am Main to Enschede train tickets online with Deutsche Bahn Intercity (DB IC) and Deutsche Bahn Regio (DB Regional).
The distance between Frankfurt am Main and Enschede is 265 km. The road distance is 374 km.
You can take a train from Frankfurt to Enschede via Essen Hbf and Dülmen, Bahnhof in around 5h 3m.