The average train between Frankfurt am Main and Iserlohn takes 3h 41m and the fastest train takes 3h 30m. The train service runs several times per day from Frankfurt am Main to Iserlohn. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Trains run every 3 hours between Frankfurt am Main and Iserlohn. The earliest departure is at 5:41 AM in the morning, and the last departure from Frankfurt am Main is at 7:08 PM which arrives into Iserlohn at 10:38 PM. All services require a transfer at Köln Messe/Deutz Bf and take an average of 3h 41m. The schedules shown below are for the next available departures.


3h 57m • 2 changes


3h 30m • 2 changes


3h 30m • 2 changes


3h 30m • 2 changes


3h 57m • 2 changes


3h 30m • 2 changes


3h 30m • 2 changes


3h 30m • 2 changes


3h 57m • 2 changes


3h 30m • 2 changes


3h 30m • 2 changes


3h 30m • 2 changes


3h 57m • 2 changes


3h 30m • 2 changes


3h 30m • 2 changes


3h 30m • 2 changes
Want to know about travelling from Frankfurt am Main to Iserlohn? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct train from Frankfurt am Main to Iserlohn. However, there are services departing from Frankfurt am Main station and arriving at Iserlohn station via Köln Messe/Deutz Bf. The journey, including transfers, takes approximately 3h 41m.
Frankfurt am Main to Iserlohn train services, operated by Deutsche Bahn Intercity (DB IC), depart from Frankfurt station.
Frankfurt am Main to Iserlohn train services, operated by Deutsche Bahn Intercity (DB IC), arrive at Hagen Hbf station.
Book your Frankfurt am Main to Iserlohn train tickets online with Deutsche Bahn Intercity (DB IC), National Express and VIAS Rail GmbH.
The distance between Frankfurt am Main and Iserlohn is 156.2 km. The road distance is 275 km.
You can take a train from Frankfurt to Iserlohn via Köln Messe/Deutz Bf, Koeln Messe/Deutz, and Hagen Hbf in around 3h 2m.