The average train between Frankfurt am Main and Itzehoe takes 5h 20m and the fastest train takes 4h 55m. The train service runs several times per day from Frankfurt am Main to Itzehoe. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Trains run every 2 hours between Frankfurt am Main and Itzehoe. The earliest departure is at 4:21 AM at night, and the last departure from Frankfurt am Main is at 11:22 PM which arrives into Itzehoe at 7:57 AM. All services require a transfer, and take on average 5h 20m. The schedules shown below are for the next available departures.

5h 11m • 1 change

5h 11m • 1 change

5h 11m • 1 change

5h 11m • 1 change

5h 16m • 1 change

5h 11m • 1 change

5h 11m • 1 change

5h 11m • 1 change

5h 16m • 1 change

5h 11m • 1 change

5h 11m • 1 change

5h 11m • 1 change

5h 36m • 1 change

5h 11m • 1 change

5h 11m • 1 change

5h 11m • 1 change

5h 36m • 1 change

5h 11m • 1 change

5h 11m • 1 change

5h 11m • 1 change
Want to know about travelling from Frankfurt am Main to Itzehoe? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct train from Frankfurt am Main to Itzehoe. However, there are services departing from Frankfurt am Main station and arriving at Itzehoe station via Hamburg Hbf. The journey, including transfers, takes approximately 5h 20m.
Frankfurt am Main to Itzehoe train services, operated by Deutsche Bahn Intercity (DB IC), depart from Frankfurt station.
Frankfurt am Main to Itzehoe train services, operated by Deutsche Bahn Intercity (DB IC), arrive at Itzehoe station.
Book your Frankfurt am Main to Itzehoe train tickets online with Deutsche Bahn Intercity (DB IC) and Nordbahn Eisenbahngesellschaft.
The distance between Frankfurt am Main and Itzehoe is 426.9 km. The road distance is 580 km.
You can take a train from Frankfurt to Itzehoe via Hamburg Hbf in around 5h.