The average train between Frankfurt am Main and Lyon takes 8h 41m and the fastest train takes 5h 56m. The train service runs several times per day from Frankfurt am Main to Lyon. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Trains run 4 times a day between Frankfurt am Main and Lyon. The earliest departure is at 6:53 AM in the morning, and the last departure from Frankfurt am Main is at 4:55 PM which arrives into Lyon at 10:59 AM. All services require a transfer at Strasbourg Bahnhof and take an average of 8h 41m. The schedules shown below are for the next available departures.

6h 6m • 1 change

6h 2m • 1 change

5h 56m • 1 change
Arrives next day

18h 4m • 1 change

6h 6m • 1 change

6h 2m • 1 change

5h 56m • 1 change
Arrives next day

18h 4m • 1 change

6h 6m • 1 change

6h 2m • 1 change

5h 56m • 1 change
Arrives next day

18h 4m • 1 change

6h 6m • 1 change

6h 2m • 1 change

5h 56m • 1 change
Arrives next day

18h 4m • 1 change
Want to know about travelling from Frankfurt am Main to Lyon? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct train from Frankfurt am Main to Lyon. However, there are services departing from Frankfurt am Main station and arriving at Lyon station via Strasbourg Bahnhof. The journey, including transfers, takes approximately 8h 41m.
Frankfurt am Main to Lyon train services, operated by Deutsche Bahn Intercity (DB IC), depart from Frankfurt station.
Frankfurt am Main to Lyon train services, operated by Deutsche Bahn Intercity (DB IC), arrive at Lyon Part Dieu station.
Book your Frankfurt am Main to Lyon train tickets online with Deutsche Bahn Intercity (DB IC) and TGV inOui.
The distance between Frankfurt am Main and Lyon is 563.3 km. The road distance is 724 km.
You can take a train from Frankfurt to Lyon Part Dieu via Strasbourg Bahnhof and Strasbourg in around 7h 2m.