Frankfurt am Main to Mesum Trains

Trip Overview

The average train between Frankfurt am Main and Mesum takes 4h 16m and the fastest train takes 3h 54m. There is a train service every few hours from Frankfurt am Main to Mesum. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.

4h 16m
Duration: 364 km
Distance: €85
Average price: Hourly
Frequency

Train

best

Take the train from Frankfurt to Münster Hauptbahnhoftrain 42 / ...

4h 26m

€67–269

Frankfurt am Main to Mesum train times

Trains run hourly between Frankfurt am Main and Mesum. The earliest departure is at 4:13 AM at night, and the last departure from Frankfurt am Main is at 11:13 PM which arrives into Mesum at 7:59 AM. All services require a transfer at Frankfurt and take an average of 4h 16m. The schedules shown below are for the next available departures.

Departing Wednesday, August 19, 2026

8:43 PM → 12:37 AM
Arrives next day
3h 54m • 2 changes
11:13 PM → 5:59 AM
Arrives next day
6h 46m • 2 changes

Departing Thursday, August 20, 2026

4:13 AM → 8:37 AM
4h 24m • 2 changes
6:43 AM → 10:59 AM
4h 16m • 2 changes
7:43 AM → 11:59 AM
4h 16m • 2 changes
8:43 AM → 12:59 PM
4h 16m • 2 changes
Show more

Departing Friday, August 21, 2026

4:13 AM → 8:37 AM
4h 24m • 2 changes
6:43 AM → 10:59 AM
4h 16m • 2 changes
7:43 AM → 11:59 AM
4h 16m • 2 changes
8:43 AM → 12:59 PM
4h 16m • 2 changes
Show more

Departing Saturday, August 22, 2026

4:13 AM → 8:59 AM
4h 46m • 2 changes
6:43 AM → 10:59 AM
4h 16m • 2 changes
7:43 AM → 11:59 AM
4h 16m • 2 changes
8:43 AM → 12:59 PM
4h 16m • 2 changes
Show more

Departing Sunday, August 23, 2026

4:13 AM → 8:59 AM
4h 46m • 2 changes

Frequently asked questions

Want to know about travelling from Frankfurt am Main to Mesum? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.