The average train between Frankfurt am Main and Mosbach takes 2h 10m and the fastest train takes 2h 2m. There is a train service every few hours from Frankfurt am Main to Mosbach. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Trains run hourly between Frankfurt am Main and Mosbach. The earliest departure is at 1:17 AM at night, and the last departure from Frankfurt am Main is at 11:20 PM which arrives into Mosbach at 1:37 AM. All services require a transfer, and take on average 2h 10m. The schedules shown below are for the next available departures.

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2h 21m • 1 changeWant to know about travelling from Frankfurt am Main to Mosbach? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct train from Frankfurt am Main to Mosbach. However, there are services departing from Frankfurt station and arriving at Mosbach, Bahnhof station via Mannheim, Hauptbahnhof station. The journey, including transfers, takes approximately 2h 10m.
Frankfurt am Main to Mosbach train services, operated by Deutsche Bahn Intercity (DB IC), depart from Frankfurt station.
Frankfurt am Main to Mosbach train services, operated by Deutsche Bahn Regio (DB Regional), arrive at Mosbach, Bahnhof station.
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The distance between Frankfurt am Main and Mosbach is 91.1 km. The road distance is 117 km.
You can take a train from Frankfurt to Mosbach, Bahnhof via Mannheim, Hauptbahnhof in around 2h 16m.