The average train between Frankfurt am Main and Plzeň Region takes 8h 20m and the fastest train takes 6h 23m. The train service runs several times per day from Frankfurt am Main to Plzeň Region. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Trains run 5 times a day between Frankfurt am Main and Plzeň Region. The earliest departure is at 4:54 AM at night, and the last departure from Frankfurt am Main is at 10:19 PM which arrives into Plzeň Region at 9:20 AM. All services require a transfer at Nürnberg Hbf and take an average of 8h 20m. The schedules shown below are for the next available departures.



6h 26m • 3 changes



6h 23m • 3 changes



6h 23m • 3 changes



6h 23m • 3 changes



6h 26m • 3 changes



6h 23m • 3 changes



6h 23m • 3 changes



6h 23m • 3 changes



6h 26m • 3 changes



6h 23m • 3 changes



6h 23m • 3 changes



6h 23m • 3 changes



6h 26m • 3 changes



6h 23m • 3 changes



6h 23m • 3 changes



6h 23m • 3 changes



6h 26m • 3 changes



6h 23m • 3 changes



6h 23m • 3 changes



6h 23m • 3 changes
Want to know about travelling from Frankfurt am Main to Plzeň Region? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct train from Frankfurt am Main to Plzeň Region. However, there are services departing from Frankfurt am Main station and arriving at Plzeň Region station via Nürnberg Hbf. The journey, including transfers, takes approximately 8h 20m.
Frankfurt am Main to Plzeň Region train services, operated by Deutsche Bahn Intercity (DB IC), depart from Frankfurt station.
Frankfurt am Main to Plzeň Region train services, operated by Deutsche Bahn Intercity (DB IC), arrive at Holysov station.
The distance between Frankfurt am Main and Plzeň Region is 326.6 km. The road distance is 451 km.
You can take a train from Frankfurt to Nyrany via Nürnberg Hbf, Schwandorf, and Holysov in around 7h 1m.