The average train between Frankfurt am Main and St. Pauli takes 4h 29m and the fastest train takes 4h 7m. The train service runs several times per day from Frankfurt am Main to St. Pauli. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Trains run every 4 hours between Frankfurt am Main and St. Pauli. The earliest departure is at 8:20 AM in the morning, and the last departure from Frankfurt am Main is at 8:20 PM which arrives into St. Pauli at 12:49 AM. All services require a transfer at Hamburg Hbf and take an average of 4h 29m. The schedules shown below are for the next available departures.


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Want to know about travelling from Frankfurt am Main to St. Pauli? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct train from Frankfurt am Main to St. Pauli. However, there are services departing from Frankfurt am Main station and arriving at St. Pauli station via Hamburg Hbf. The journey, including transfers, takes approximately 4h 29m.
Frankfurt am Main to St. Pauli train services, operated by Deutsche Bahn Intercity (DB IC), depart from Frankfurt station.
Frankfurt am Main to St. Pauli train services, operated by Deutsche Bahn Intercity (DB IC), arrive at Hamburg Hbf station.
Book your Frankfurt am Main to St. Pauli train tickets online with Deutsche Bahn Intercity (DB IC) and Hamburger Verkehrsverbund (HVV).
The distance between Frankfurt am Main and St. Pauli is 392.6 km. The road distance is 516 km.
Deutsche Bahn Intercity (DB IC) operates a train from Frankfurt to Hamburg Hbf hourly. Tickets cost €90–400 and the journey takes 3h 43m.