The average train between Frankfurt am Main and Wertheim takes 2h 17m and the fastest train takes 1h 58m. There is a train service every few hours from Frankfurt am Main to Wertheim. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Trains run hourly between Frankfurt am Main and Wertheim. The earliest departure is at 4:54 AM at night, and the last departure from Frankfurt am Main is at 8:57 PM which arrives into Wertheim at 11:15 PM. All services require a transfer, and take on average 2h 17m. The schedules shown below are for the next available departures.

2h 36m • 1 change

2h 31m • 1 change

2h 27m • 1 change

1h 58m • 1 change

2h 36m • 1 change

2h 31m • 1 change

2h 27m • 1 change

1h 58m • 1 change

2h 36m • 1 change

2h 31m • 1 change

2h 27m • 1 change

1h 58m • 1 change

2h 39m • 1 change

1h 58m • 1 change

1h 58m • 1 change

1h 58m • 1 change
Want to know about travelling from Frankfurt am Main to Wertheim? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct train from Frankfurt am Main to Wertheim. However, there are services departing from Frankfurt am Main station and arriving at Wertheim station via Aschaffenburg Hbf. The journey, including transfers, takes approximately 2h 17m.
Frankfurt am Main to Wertheim train services, operated by Deutsche Bahn Intercity (DB IC), depart from Frankfurt station.
Frankfurt am Main to Wertheim train services, operated by Deutsche Bahn Intercity (DB IC), arrive at Wertheim, Bahnhof station.
Book your Frankfurt am Main to Wertheim train tickets online with Deutsche Bahn Intercity (DB IC) and Deutsche Bahn Regio (DB Regional).
The distance between Frankfurt am Main and Wertheim is 71.1 km. The road distance is 113 km.
You can take a train from Frankfurt to Wertheim, Bahnhof via Aschaffenburg Hbf in around 2h 31m.